Consistently, in severe cases of COVID-19, Tomic et al. (2021) observed a significant decrease in the expression of specific autophagy-related genes, including ULK1, ATG5, UV radiation resistance-associated gene protein (UVRAG), activating molecule in BECN1-regulated autophagy protein 1 (AMBRA1), PIK3C3, and LC3, in comparison to healthy individuals [158]. The gene discussed is UVRAG; the disease is COVID-19.