These molecules interact with toll-like receptors (TLRs) present on the surface of antigen-presenting cells (APCs) and monocytes, leading to the expression of genes associated with pro-inflammatory interleukins (IL, IL-1, IL-6, IL-8, IL-12, and IL-18), tumor necrosis factor-alpha (TNF-α), and interferons (IFNs like IFN-y) and anti-inflammatory (IL-10) pathways and acquired immunity [4,5]; these processes are usually observed during the initial stages of sepsis [6,7,8]. Here, TNF is linked to Sepsis.