For instance, increased endogenous activation of NF-κB as well as TNF-α and IL-1β release by PBMC in the preeclampsia-affected group compared with the normotensive pregnant women was confirmed, and SB was illustrated to decrease the levels of NF-κB and the expression of pro-inflammatory cytokines (TNF-α and IL-1β) in preeclamptic women [179]. This evidence concerns the gene TNF and preeclampsia.