The authors also inferred that the extract might be targeting the inflammasome formation (a significant target under study for the treatment of colitis) as a reduction in the key proteins NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3; NOD, nucleotide-binding oligomerization domain; LRR, leucine-rich repeat), ASC (apoptosis-associated speck-like protein containing a CARD), and caspase-1 was observed. The gene discussed is NLRP3; the disease is colitis.