The significant correlations of MPST with GOT2, SLC1A1, and SLC7A11 and MPST with GOT1 and SLC1A1 were also verified in EGFRMut and KRASMut tumors, respectively (Table 3 and Supplementary Figure S2), suggesting that cysteine catabolism routes through MST and CAT/GOT enzymes with the production of H2S and through CDO1 and CAT/GOT enzymes are pivotal in some subsets of NSCLC. Here, SLC7A11 is linked to non-small cell lung carcinoma.