Accumulating evidence has shown that RNA m6A modification widely regulates immunological processes.[48] It has also been determined that YTHDF2 deficiency in tumor‐associated macrophages suppresses tumor growth by reprogramming tumor‐associated macrophages toward an antitumoral phenotype and increasing their antigen cross‐presentation ability, which in turn enhances CD8+ T‐cell‐mediated antitumor immunity.[49] Ma et al. Here, CD8A is linked to neoplasm.