In addition, flow cytometry and enzyme‐linked immunosorbent assay (ELISA) showed that cell surface‐localized PD‐L1 (sPD‐L1) and the secreted form of VEGFA (sVEGFA) were significantly lower in HCC cells with relatively lower YTHDF2 expression (Figure 3D,E). Here, SPDL1 is linked to hepatocellular carcinoma.