Additionally, the enhanced killing ability of CD8+ T cells induced by YTHDF2 knockdown in HCC cells was reversed by overexpressing PD‐L1, and opposite trends were observed in HLF/OE‐YTHDF2 and Hepa1‐6/OE‐YTHDF2 cells (Figure 3G; Figure S5F,G, Supporting Information). Here, YTHDF2 is linked to hepatocellular carcinoma.