Overall, our results suggest that OA can help treat obesity by regulating PPAR\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\gamma$$\end{document}γ and activating the PPAR signaling pathway. This evidence concerns the gene PPARA and obesity due to melanocortin 4 receptor deficiency.