GPT and hepatocellular carcinoma: Additionally, multivariate analyses identified patient risk factors associated with the occurrence of Grades 2–4 abnormalities in ALT/AST/BIL(T), namely age > 70 years old, presence of HCC, BIL(T) > 1.2 mg/dL, eGFR < 60 mL/min/1.73 m2, and FIB-4 > 3.25 (Table 3).