AP infections can trigger a systemic inflammatory response that has been associated with increased oxidative stress and high blood levels of inflammatory biomarkers such as C-reactive protein (CRP), interleukin (IL)-1, IL-2, and IL-6.17, 18, 19, 20, 21, 22 In severe cases, this inflammatory response may even evolve into septicaemia and increase the risk of pathologic conditions such as atherosclerosis,23 cardiovascular disease, and diabetes.24 The gene discussed is CRP; the disease is bacterial infectious disease with sepsis.