ENPP2 and Alzheimer disease: The study reported ten proteins increased in AD but not in DLB or PD (pro-orexin, ENPP2, LAMP1, transthyretin, ApoE, carnosine dipeptidase 1, ubiquitin, caboxypeptidase E, malate dehydrogenase, and insulin-like growth factor–binding protein 2) as well as 13 additional proteins that were elevated in both AD and DLB compared with controls, including CH3L1.