Gastrokine 2 stimulates apoptosis of gastric cancer cells by inhibiting NF-κB signaling and by activating JNK signaling pathway (Menheniott et al. 2016; Zhang et al. 2019a), while granzymes are expressed on cytotoxic T lymphocytes and NK cells to induce cell death (Voskoboinik et al. 2015). Here, MAPK8 is linked to gastric cancer.