For example, miR-124, miR-125, miR-320, miR-1301 directly target 3′-UTR of STAT3 and inhibit cell cycle progression, proliferation, migration and invasion in bladder cancer [88], gastric cancer [89], lung adenocarcinoma and colorectal cancer [90, 91]. The gene discussed is STAT3; the disease is urinary bladder carcinoma.