Consequently, tumors derived from a mixture of CRC cells (CT26.WT or CMT93) with Miip knockdown and adipocytes (3T3-L1 cells) were notably larger (Fig. 4b, c and Additional file 1: Fig. S6c, d) and heavier (Fig. 4d and Additional file 1: Fig. S6e) than tumors from the scramble group, particularly during the later stages post-injection. The gene discussed is MIIP; the disease is colorectal carcinoma.