Consistent with the increased secretion of FFAs from beige adipocytes in the tumor microenvironment (TME), cells incubated with adipocyte CM pretreated with MIIP+/− cancer cell CM exhibited higher expression levels of FFA transporters, CD36 and FABP4, compared to cells treated with WT (MIIP+/+) CM (Fig. 5h). This evidence concerns the gene MIIP and neoplasm.