On protein level, significantly reduced levels of the secreted proinflammatory cytokines IL6 (p = 0.0023; Fig. 6a) and TNFα (p = 0.0022; Fig. 6b) were detected at 72 h and 48 h respectively (since start of exposure 1) in the bro-ALI model following exposure to wood smoke (n = 6 independent experiments per exposure condition). The gene discussed is TNF; the disease is acute respiratory distress syndrome.