SMN1 and laryngotracheoesophageal cleft: The results showed that oxymatrine, matrine, oxysophocarpine, sophocarpine, sophoridine and cytisine of SMA could form the best complex with 2W96, 2CCH and 1O96 target proteins, and to further verify the therapeutic effect of SMA in LC A549 cell, which also can provide a reliable reference basis that SMA were potential candidates in treating LC.