The highly expressed genes (AP3B2, STAT3, TSPO, S100A9, and GNS) were primarily enriched in “fatty acid biosynthesis”, “glycosaminoglycan degradation”, “legionellosis”, “neutrophil extracellular trap formation”, “lysosome”, “homologous recombination”, “mismatch repair”, “ferroptosis”, and “leishmaniasis”. The gene discussed is GNS; the disease is leishmaniasis.