Cell type associations also indicated that CSC fractions correlated negatively with the majority of activating immune cells, including CD8 + T, cytotoxic, and NK T-cells, and positively with suppressive immune cells, including Th2 cells, myeloid-derived suppressor cells, tumor-associated macrophages, and naïve CD8 + T-cells (Fig. 2g). The gene discussed is CD8A; the disease is neoplasm.