Ti analysis showed that an increase of CD8 GZMK+ in tumor samples was a predictor of favorable GOLP response (Fig. 5F), and a higher post-to-pre GOLP ratio of CD8 GZMK+ was significantly correlated with more shrinkage of tumor (R = 0.92, P = 0.001; Fig. 5G). This evidence concerns the gene CD8A and neoplasm.