PDCD1 and infantile convulsions and choreoathetosis: Fibroblast growth factor receptor (FGFR) signaling and/or the programmed death 1 (PD1)/ programmed death ligand-1 (PD-L1) pathway are abnormally activated in some patients with iCCA, which prompted calls for targeted therapy at FGFR signaling and/or immune checkpoint blockade (ICB).