In addition, higher expression of CD274, HLA-A, PCNA, FGF11, and FGF18 in tumor cells before treatment was a favorable predictor of tumor shrinkage (Fig. 3B; Supplementary Data 3), and gene set enrichment analysis (GSEA) showed that PD1 signaling, positive regulation of vasculature development and signaling by KIT in disease were enriched in the tumor cells from patients with a good response to GOLP therapy (Fig. 3C). Here, FGF18 is linked to neoplasm.