CD8A and malignant colon neoplasm: For example, CD36, an FA transport receptor and lipid oxidation scavenging receptor, increases expression of CD36 in melanoma and colon cancer cell lines, induces lipid peroxidation and increased fatty acid uptake, and causes functional inhibition and iron death in CD8+ CTL cells in a CD36-dependent manner (Fig. 2) [64, 65].