HSD17B4 and retinal degeneration: In contrast to the early onset retinal degeneration observed in global Mfp2-knockout mice (Das et al. 2021b), mice only lacking Mfp2 or Pex5 in photoreceptors and bipolar cells display a much milder phenotype, with reduced visual acuity over time but normal retinal morphology and photoreceptor function (Swinkels et al. 2022).