The authors determined that electrical myotonia was much more significant in IMNM than other forms of myopathy and could help improve the diagnosis of IMNM, particularly in cases where the disease has a chronic and indolent course, and where patients test negative for autoantibodies against hydroxy-3-methylglutaryl-coenzyme-A reductase (HMGCR) or signal recognition particle (SRP54) [37]. This evidence concerns the gene HMGCR and Myotonia.