HMGCR and myopathy: Additionally, the same method identified genes uniquely overexpressed in various MSA-defined myositis subtypes, such as APOA4 was found to be significantly overexpressed in anti-HMGCR positive myopathy, and mucosal vascular address in cell adhesion molecule 1 (MADCAM1) was found overexpressed in anti-Mi2 positive DM.