TH and hydrops fetalis: The results indicated that compared to C-MitoCtrl, C-MitoHF increased the number of TH-positive nerve fibers (Fig. 9A, B) and GAP43-positive sprouting nerves in the myocardium of HF mice (Fig. 9C, D), which were ameliorated by reducing endothelial cGAS in the SFO of HF mice (Fig. 9A–D).