In conclusion, the changes in the expression of lncRNAs (IDH1-AS1, PCAT14, FTX, DANCR, PRKCQ-AS1, SNHG8, TPT1-AS1)and mRNAs (CXCR4, RABL6, OPN3, SYBU, IDH1, NOP10) may possibly affect endometrial function in patients with PCOS before the implantation window, probably resulting in implantation failure of the embryo. The gene discussed is IDH1; the disease is polycystic ovary syndrome.