On multivariate analyses, patients with bacterial infections were older (adjusted odds ratio [aOR] 1.024, 95% confidence interval [CI] 1.016–1.032, p < 0.001), had more neurological diseases (aOR 2.07, 95% CI 1.34–3.18, p = 0.001), hematological diseases (aOR 2.13, 95% CI 1.26–3.59, p = 0.005), and malignancy (aOR 2.50, 95% CI 1.38–4.52, p = 0.002), higher white cell count (aOR 1.07, 95% CI 1.02–1.13, p = 0.005), and C reactive protein (aOR 1.04, 95% CI 1.02–1.07, p = 0.002), and higher proportion required intensive care (aOR 4.94, 95% CI 3.59–6.80, p < 0.001). This evidence concerns the gene CRP and bacterial infectious disease.