For the fifth dataset GSE18105, the mean value (7.569) of CXCL8 in the normal cell (0,0) is smaller than the mean value (10.72) of CXCL8 in CRC cells (1,1); the mean value (11.6) of PSMC2 in (0,0) is smaller than the mean value (12.46) of PSMC2 in cell (1,1); the mean value (10.69) of SLC20A1 in (0,0) is larger than the mean value (9.725) in cell (1,1). The gene discussed is CXCL8; the disease is colorectal carcinoma.