For the sixth dataset GSE41258, the mean value (686.8) of CXCL8 in the normal cell (0,0) is significantly smaller than the mean value (1133) of CXCL8 in CRC cells (1,1); the mean value (49.8) of PSMC2 in (0,0) is ten times smaller than the mean value (534.3) of PSMC2 in cell (1,1); the mean value (545.7) of SLC20A1 in (0,0) is larger than the mean value (459.1) in cell (1,1). The gene discussed is SLC20A1; the disease is colorectal carcinoma.