The half-maximal effective concentration of PD-L1 antibodies was significantly lower than that of PD-1 antibodies, suggesting that PD-L1 antibodies may be a more effective inhibitor than PD-1 antibodies.[24] PD-L1 protein is an important transmodel immunoglobulin on the cell membrane that plays a crucial role in the formation of the tumor microenvironment and tumor immune escape. This evidence concerns the gene CD274 and neoplasm.