Wang et al reported that E2F7 could rescue the inhibitory effects of sh-SNHG6 or miR-26a-5p mimics on cell migration and EMT, critical for LUAD cell metastasis and EMT.[45] Furthermore, the dysregulation of the SNHG6/miR-26a-5p/E2F7 axis was positively associated with a more advanced stage, larger tumor size, and worse OS in LUAD patients.[45] Similarly, by univariate and multivariate Cox regression analyses, GEPIA database and immunohistochemical analysis, we also observed that E2F7 was positively associated with larger tumors and higher TNM stages. Here, SNHG6 is linked to neoplasm.