Q > 0.3 means that the clustering structure is significant, S > 0.5 clustering class is reasonable, and S > 0.7 means that the clustering is convincing.[13] The co-cited references were divided into 17 clusters: #0 insulin sensitivity, #2 heart failure, #3 lifestyle intervention, #4 renal dysfunction, #5 Asian Indian, #6 gut microbiota, #7 diagnosing diabetes, #8 alt ratio, #9 1-hour ogtt glucose, #10 cardiovascular safety, #11 statin therapy, #12 white matter hyperintensities, #13 glp-1 receptor agonist, #14 physical activity promotion program, #15 polycystic ovary syndrome, and #16 d level. The gene discussed is GLP1R; the disease is diabetes mellitus.