PRKDC and colorectal cancer: KRT80 expression promoted proliferation, migration, invasion and EMT of colorectal cancer cells by interacting with PRKDC via Akt pathway.5 Zhao et al.15 demonstrated that NSCAT1 competed with miR-1245 to suppress the inhibitory effects of miR-1245 on the translation of KRT80 in head and neck squamous cancer cells.