We identified Rbfox1 (also known as A2BP1) as a key trans-acting RNA splicing regulator in injured DRG neurons following SNL, Rbfox1 is highly expressed in the brain, cardiac muscle, and skeletal muscle, and it has been implicated in various neurodevelopmental and neuropsychiatric conditions, including epilepsy, intellectual disability, autism, and schizophrenia [[21], [22], [23]]. The gene discussed is RBFOX1; the disease is Intellectual disability.