INS and diabetes mellitus: During the intervention period, the changes in the overall diabetes medications (insulin, GLP-1RA, and oral hypoglycemic agents) were observed as follows: at 12 weeks, treatment was continued in 28 (60%) out of 47 patients, reduced in 10 (21%), and intensified in 9 (19%); at 24 weeks, treatment was continued in 21 (45%) patients, reduced in 15 (32%), and intensified in 11 (23%).