The AUCs for disease duration, CRP and fibrinogen in distinguishing tophus in gout were 0.753 (sensitivity of 0.923, specificity of 0.558, p = 0.003), 0.703 (sensitivity of 0.769, specificity of 0.681, p = 0.017) and 0.701 (sensitivity of 0.615, specificity of 0.770, p = 0.018) (Fig. 6). This evidence concerns the gene CRP and gout.