Through a succession of comparisons between the PWAS, SMR, TWAS and FOCUS results, 5 (CD38, GPNMB, RAB29, TMEM175, TTC19) of the 16 proteome-wide significant genes were supported by TWAS and FOCUS, suggesting that these genes hold the potential to become therapeutic targets for PD. Here, TMEM175 is linked to Parkinson disease.