INS and type 2 diabetes mellitus: Findings from a previous meta-analysis suggested that insulin treatment increased the risk of DR (30), which was similar to results from a hospital-based study (n=134), showing that insulin was associated with a higher risk of DR in people with type 2 diabetes, compared to people treated with other antidiabetic drugs (OR 2.4, 95%CI 0.9-6.6) (36).