ALB and diabetic kidney disease: Similarly, SII was associated with a 4.2-fold increased risk of DKD-non-Alb+DKD stage 3 Alb (P < 0.01), and the increased risk of DKD-non-Alb+DKD stage 3 Alb from Q1 to Q4 was also statistically significant in fully adjusted model 4 (P for trend < 0.01).