The expression of human ATXN3 with 10 CAG repeats, below the threshold to cause Machado-Joseph disease, in C. elegans GABAergic neurons under the unc-47 promoter results in motor deficits and reduced lifespan, but not neurodegeneration (Table 6) (Fardghassemi et al., 2017). The gene discussed is ATXN3; the disease is Machado-Joseph disease.