Independent prognostic factors were IDH mutation (OR = 0.380; 95% CI, 0.263–0.550), older age (OR = 1.573; 95% CI, 1.350–1.834), high preoperative Karnofsky performance score (OR = 0.976; 95% CI, 0.971–0.982), high tumor grade (OR = 1.329; 95% CI, 1.110–1.592), and motor dysfunction as the PS (OR = 1.636; 95% CI, 1.147–2.332). The gene discussed is IDH1; the disease is neoplasm.