The results indicated that in the high-risk group, pathways such as alcoholism, cell cycle, cellular senescence, IL-17 signaling pathway, and bladder cancer were significantly enriched, while pathways significantly enriched in the low-risk group included regulation of lipolysis in adipocytes, chemical carcinogenesis-DNA adducts, chemical carcinogenesis-receptor activation, the complement and coagulation cascades, herpes simplex virus 1 infection, and peroxisome. This evidence concerns the gene IL17A and alcohol drinking.