ACEI: angiotensin-converting enzyme inhibitors; ADM: antidiabetics; AF: atrial fibrillation; APLT: antiplatelet; BB: beta-blockers; CCB: calcium channel blockers; DIU: diuretics; DM: diabetes mellitus, FHOS: family history of stroke; IHD: ischemic heart disease; HTN: hypertension; HPLD: hyperlipidemia; HU: hyperuricemia; NIHSS: National Institute of Health Stroke Scale; N: number of patients. The gene discussed is ACE; the disease is Hypertension.