These specific genes are those associated with AD pathology such as APP, PSEN-1, microtubule-associated protein tau (MAPT), glycogen synthase kinase 3 beta (GS3K-β), protein phosphatase (PP2A), and apolipoprotein E (APOE; Yokoyama et al., 2017). The gene discussed is MAPT; the disease is Alzheimer disease.