IL18R1 and neuroblastoma: Consequently, the molecular mechanisms of HG-NB that impact prognosis include chemokine-mediated signaling pathways, neutrophil chemotaxis, inflammatory responses, extracellular space and extracellular region, integral components of the plasma membrane, chemokine activity, oxygen binding, CCR chemokine receptor binding, neuroactive ligand-receptor interactions, cytokine-cytokine receptor interactions, and cAMP signaling pathways.