Similarly, the production of CXCL10, a pro-inflammatory cytokines relevant for the recruitment of antigen-specific T-cells into the tumor tissues (66) and mainly dependent on IFNα-IFNAR autocrine/paracrine signaling in pDCs (67), resulted consistently reduced by SN-mel as shown by intracellular flow cytometry (Figures 4D, E). The gene discussed is IFNAR1; the disease is neoplasm.