Baseline uMCP-1 was significantly higher in active nephritis (AN) compared with active disease without nephritis (ANR), inactive disease (ID), healthy subjects (HC), and rheumatoid arthritis (RA) (p<0.001), but did not differ from DN and showed a good correlation with rSLEDAI and SLEDAI (r = 0.52 and 0.47, p<0.001), but not correlated with serum MCP-1 levels. The gene discussed is CCL2; the disease is nephritis.