Additionally, ZBP1, XAF1, IFI44L, SOCS1, and PARP14 were notably high in HighPANscore cells, aligning with our observations of upregulated expression of IFI44, IFIH1, IFIT1, IFIT2, and RSAD2 in lung tissues from sepsis-induced animal models. This evidence concerns the gene XAF1 and Sepsis.