There was no statistically significant difference between the uterine volume of adenomyosis and the expression of COX-2 (P = 0.642), WBP2 (P = 0.501), IFITM3 (P = 1.000), and SFRP4 (P = 0.501) in the high expression group compared to the low expression group (Table 4). This evidence concerns the gene SFRP4 and adenomyosis.