Moreover, NLR emerged as a more efficient biomarker in the prediction of NASH and liver fibrosis than C reactive protein (CRP), and was independently correlated with histological changes which are typical of NAFLD, such as ballooning degeneration, lobular inflammation, steatosis and fibrosis degree (Yilmaz et al., 2015). This evidence concerns the gene CRP and metabolic dysfunction-associated steatohepatitis.