Using the generated VCF file and a set of phenotypes (HP:0001561:Polyhydramnios, HP:0001622: Premature birth), the Exomiser tool identified a potential disease-causing variant (c.1271 + 4_1271 + 7delAGTA) that could disrupt the coding sequence of MAGED2. This variant is predicted to be deleterious and is associated with antenatal Bartter syndrome, a condition characterized by fetal polyuria, polyhydramnios, and prematurity. This evidence concerns the gene MAGED2 and Bartter syndrome.