CEACAM5 and neoplasm: Multivariate Cox regression analysis indicated that pathological differentiation (P = 0.014), pathological N stage (P = 0.006), 4 ~ 6 months adjuvant ChT (P = 0.025) were independent prognostic factors for OS, the tumor distance from the anal verge (P = 0.029), pathological differentiation (P = 0.001) were independent prognostic factors for LRFS, CEA levels (P = 0.027), pathological N stage (P = 0.004), 4 ~ 6 months adjuvant ChT (P = 0.006) were independent prognostic factors for DMFS.