CEACAM5 and metastasis: Univariate Cox regression analysis indicated that preoperative CEA levels, pathological differentiation, pathological N stage, and pathological TNM (tumor-node-metastasis) stage were associated with OS (P < 0.05), pathological differentiation were associated with LRFS (P < 0.05), preoperative CEA levels, pathological N stage, pathological TNM stage were associated with DMFS (P < 0.05).