CEACAM5 and neoplasm: We reported the outcomes of multivariate Cox regression analysis which demonstrated that pathological differentiation、pathological N stage, 4 ~ 6 months adjuvant ChT were independent prognostic factors for OS, the tumor distance from the anal verge, and the pathological differentiation were independent prognostic factors for LRFS, preoperative CEA levels, pathological N stage, and 4 ~ 6 months adjuvant ChT were independent prognostic factors for DMFS.