In the present study, it was discovered that the expression of the BAMBI gene was down-regulated in the MII-CC of the PCOS compared to MII-CC of the non-PCOS groups, and this decrease in BAMBI expression in PCOS women can result in an arrested cell cycle in the primary stage, which may be the cause of lower oocyte quality in those patients. This evidence concerns the gene BAMBI and polycystic ovary syndrome.