CRP, as an indicator of inflammation, is also abnormally expressed in medicine infections (urology, sepsis, meningitis, osteomyelitis) and surgical disorders (acute appendicitis, tissue injuries, postoperative infections), cardiovascular disorders, systemic infectious diseases, as well as malignant disorders, and even diseases related to intensive care units, and lack some specificity [29]. The gene discussed is CRP; the disease is appendicitis.